Aug 17, 2023 · Another study compared Clonidine to zopiclone for insomnia treatment in chronic pain patients and found Clonidine to be more effective in improving sleep quality
PREVALENCE
One of two controlled studies suggested benefit from clonidine versus placebo
What to Know About Clonidine for Sleep Clonidine for insomnia
Under clonidine, the level of nocturnal hypoxemia improved in six
Clonidine in particular has also received notoriety for being prescribed as a sleep aid in children with or without ADHD
J Am Acad Child Adolesc
The CSHQ is the most commonly used parent-rated scale to assess sleep disturbance in pediatric populations
Crossref Two cross-over studies, one open-label case series, and seven case reports were identified
One study showed clonidine to be ineffective in improving performance of a single task, at a specific point in time, in a small number of subjects
It has a low risk of adverse effects and dependency
For patients medicated with clonidine, it took longer to be wide awake (drowsiness time: 26 minutes and 13 seconds for Two open-label studies examined the use of clonidine for disordered sleep in children without ASD, finding the prescription made it easier for participants to fall and stay asleep, with few Clonidine reduced insomnia; and melatonin also exhibited a positive response, with reduced sleep latency, higher total sleep time, and higher sleep efficiency
All studies had a small number of participants, ranging from seven to 16 people per study and had a cross-over design
1 mg once or twice daily, with a gradual increase up to 2
The studies have, however, found similar prevalence in SB for people with or without occlusal interferences, and SB
An open labeled retrospective study of clonidine for the treatment of insomnia, and/or hyperactivity, inattention, mood disorder, and aggressive behaviours in a cohort of 19 children with ASD showed that clonidine was effective in reducing sleep initiation latency and nighttime awakening
Common clonidine side effects may include: drowsiness, dizziness; feeling tired or irritable; dry mouth; constipation, loss of appetite; or
The patients were randomly assigned to receive placebo or clonidine (2 microg/kg oral) the night before and the next morning 2 h before surgery
Clonidine is an alpha-2 adrenergic agonist
but alpha-2-adrenergic agonists (i